After stimulus, cells were treated as was previously described23. well as the involvement of LRP1 in this process in the human Mller glial-derived cell line (MIO-M1). We found that IGF-1 produced GLUT1 translocation to the PM, in a time-dependent manner involving the intracellular signaling activation of MAPK/ERK and PI3K/Akt pathways, and generated a significant glucose … Continue reading After stimulus, cells were treated as was previously described23